Systematic evaluation of C. elegans lincRNAs with CRISPR knockout mutants

BACKGROUND: Long intergenic RNAs (lincRNAs) play critical roles in eukaryotic cells, but systematic analyses of the lincRNAs of an animal for phenotypes are lacking. We generate CRISPR knockout strains for Caenorhabditis elegans lincRNAs and evaluate their phenotypes. RESULTS: C. elegans lincRNAs de...

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Detalles Bibliográficos
Autores principales: Wei, Shuai, Chen, He, Dzakah, Emmanuel Enoch, Yu, Bin, Wang, Xiaolin, Fu, Tao, Li, Jingxin, Liu, Lei, Fang, Shucheng, Liu, Weihong, Shan, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325887/
https://www.ncbi.nlm.nih.gov/pubmed/30621757
http://dx.doi.org/10.1186/s13059-018-1619-6

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