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OCMA: Fast, Memory-Efficient Factorization of Prohibitively Large Relationship Matrices
Matrices representing genetic relatedness among individuals (i.e., Genomic Relationship Matrices, GRMs) play a central role in genetic analysis. The eigen-decomposition of GRMs (or its alternative that generates fewer top singular values using genotype matrices) is a necessary step for many analyses...
Autores principales: | Xiong, Zhi, Zhang, Qingrun, Platt, Alexander, Liao, Wenyuan, Shi, Xinghua, de los Campos, Gustavo, Long, Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325911/ https://www.ncbi.nlm.nih.gov/pubmed/30482799 http://dx.doi.org/10.1534/g3.118.200908 |
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