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Dosage Compensation and Gene Expression of the X Chromosome in Sheep

Ohno’s hypothesis predicts that the expression of the single X chromosome in males needs compensatory upregulation to balance its dosage with that of the diploid autosomes. Additionally, X chromosome inactivation ensures that quadruple expression of the two X chromosomes is avoided in females. These...

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Detalles Bibliográficos
Autores principales: Duan, Jingyue (Ellie), Flock, Kaleigh, Jue, Nathanial, Zhang, Mingyuan, Jones, Amanda, Seesi, Sahar Al, Mandoiu, Ion, Pillai, Sambhu, Hoffman, Maria, O’Neill, Rachel, Zinn, Steven, Govoni, Kristen, Reed, Sarah, Jiang, Hesheng, Jiang, Zongliang (Carl), Tian, Xiuchun (Cindy)
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325915/
https://www.ncbi.nlm.nih.gov/pubmed/30482800
http://dx.doi.org/10.1534/g3.118.200815