Intratumor heterogeneity and tissue distribution of KRAS mutation in non-small cell lung cancer: implications for detection of mutated KRAS oncogene in exhaled breath condensate

PURPOSE: Mutated KRAS oncogene in exhaled breath condensate (EBC) can be a genetic marker of non-small cell lung cancer (NSCLC). However, a possibility of inhomogeneous distribution in cancer tissue and intratumor heterogeneity of KRAS mutation may decrease its significance. We investigated a status...

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Detalles Bibliográficos
Autores principales: Kordiak, Jacek, Szemraj, Janusz, Grabska-Kobylecka, Izabela, Bialasiewicz, Piotr, Braun, Marcin, Kordek, Radzisław, Nowak, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article – Clinical Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325989/
https://www.ncbi.nlm.nih.gov/pubmed/30368666
http://dx.doi.org/10.1007/s00432-018-2779-1

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