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The Site-Specific Amino Acid Preferences of Homologous Proteins Depend on Sequence Divergence
The propensity of protein sites to be occupied by any of the 20 amino acids is known as site-specific amino acid preferences (SSAP). Under the assumption that SSAP are conserved among homologs, they can be used to parameterize evolutionary models for the reconstruction of accurate phylogenetic trees...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326188/ https://www.ncbi.nlm.nih.gov/pubmed/30496400 http://dx.doi.org/10.1093/gbe/evy261 |