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Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors
Standard treatment, unfortunately, yields a poor prognosis for patients with primary or metastatic cancers in the central nervous system, indicating a necessity for novel therapeutic agents. Immunotoxins (ITs) are a class of promising therapeutic candidates produced by fusing antibody fragments with...
Autores principales: | Yu, Xin, Dobrikov, Mikhail, Keir, Stephen T., Gromeier, Matthias, Pastan, Ira H., Reisfeld, Ralph, Bigner, Darell D., Chandramohan, Vidyalakshmi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326518/ https://www.ncbi.nlm.nih.gov/pubmed/30625226 http://dx.doi.org/10.1371/journal.pone.0210608 |
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