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Double-Modified Glycopolymers from Thiolactones to Modulate Lectin Selectivity and Affinity
[Image: see text] Multivalent glycomaterials show high affinity toward lectins but are often nonselective as they lack the precise 3-D presentation found in native glycans. Here, thiolactone chemistry is exploited to enable the synthesis of glycopolymers with both a primary binding (galactose) and a...
Autores principales: | Wilkins, Laura E., Badi, Nezha, Du Prez, Filip, Gibson, Matthew I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326524/ https://www.ncbi.nlm.nih.gov/pubmed/30662815 http://dx.doi.org/10.1021/acsmacrolett.8b00825 |
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