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A Highly Reactive Imidazolium-Bridged Dinucleotide Intermediate in Nonenzymatic RNA Primer Extension
[Image: see text] Because of its importance for the origin of life, the nonenzymatic copying of RNA templates has been the subject of intense study for several decades. Previous characterizations of template-directed primer extension using 5′-phosphoryl-2-methylimidazole-activated nucleotides (2-MeI...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326528/ https://www.ncbi.nlm.nih.gov/pubmed/27552367 http://dx.doi.org/10.1021/jacs.6b07977 |