Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α(4)β(7) integrin antibody

A functional HIV cure requires immune reconstitution for lasting viremia control. A major immune dysfunction persisting in HIV infection is the impairment of T helper cell migration and homing to lymphoid tissues such as GALTs (gut-associated lymphoid tissues). ART (antiretroviral therapy) does not...

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Detalles Bibliográficos
Autores principales: He, Sijia, Fu, Yajing, Guo, Jia, Spear, Mark, Yang, Jiuling, Trinité, Benjamin, Qin, Chaolong, Fu, Shuai, Jiang, Yongjun, Zhang, Zining, Xu, Junjie, Ding, Haibo, Levy, David N., Chen, Wanjun, Petricoin, Emanuel, Liotta, Lance A., Shang, Hong, Wu, Yuntao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326757/
https://www.ncbi.nlm.nih.gov/pubmed/30662943
http://dx.doi.org/10.1126/sciadv.aat7911

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