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BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site

Prokaryotes evolved numerous systems that defend against predation by bacteriophages. In addition to well-known restriction-modification and CRISPR-Cas immunity systems, many poorly characterized systems exist. One class of such systems, named BREX, consists of a putative phosphatase, a methyltransf...

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Detalles Bibliográficos
Autores principales: Gordeeva, Julia, Morozova, Natalya, Sierro, Nicolas, Isaev, Artem, Sinkunas, Tomas, Tsvetkova, Ksenia, Matlashov, Mikhail, Truncaitė, Lidija, Morgan, Richard D, Ivanov, Nikolai V, Siksnys, Virgis, Zeng, Lanying, Severinov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326788/
https://www.ncbi.nlm.nih.gov/pubmed/30418590
http://dx.doi.org/10.1093/nar/gky1125