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The RecB helicase-nuclease tether mediates Chi hotspot control of RecBCD enzyme
In bacteria, repair of DNA double-strand breaks uses a highly conserved helicase–nuclease complex to unwind DNA from a broken end and cut it at specific DNA sequences called Chi. In Escherichia coli the RecBCD enzyme also loads the DNA strand-exchange protein RecA onto the newly formed end, resultin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326792/ https://www.ncbi.nlm.nih.gov/pubmed/30445486 http://dx.doi.org/10.1093/nar/gky1132 |