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ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci
Quantitative trait locus (QTL) mapping of molecular phenotypes such as metabolites, lipids and proteins through genome-wide association studies represents a powerful means of highlighting molecular mechanisms relevant to human diseases. However, a major challenge of this approach is to identify the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326795/ https://www.ncbi.nlm.nih.gov/pubmed/30239796 http://dx.doi.org/10.1093/nar/gky837 |