Cargando…
ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci
Quantitative trait locus (QTL) mapping of molecular phenotypes such as metabolites, lipids and proteins through genome-wide association studies represents a powerful means of highlighting molecular mechanisms relevant to human diseases. However, a major challenge of this approach is to identify the...
Autores principales: | Stacey, David, Fauman, Eric B, Ziemek, Daniel, Sun, Benjamin B, Harshfield, Eric L, Wood, Angela M, Butterworth, Adam S, Suhre, Karsten, Paul, Dirk S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326795/ https://www.ncbi.nlm.nih.gov/pubmed/30239796 http://dx.doi.org/10.1093/nar/gky837 |
Ejemplares similares
-
Prioritization of candidate cancer genes—an aid to oncogenomic studies
por: Furney, Simon J., et al.
Publicado: (2008) -
Commonality of functional annotation: a method for prioritization of candidate genes from genome-wide linkage studies(†)
por: Shriner, Daniel, et al.
Publicado: (2008) -
Coexisting/Coexpressing Genomic Libraries (CoGeL) identify interactions among distantly located genetic loci for developing complex microbial phenotypes
por: Nicolaou, Sergios A., et al.
Publicado: (2011) -
Prioritizing tests of epistasis through hierarchical representation of genomic redundancies
por: Cowman, Tyler, et al.
Publicado: (2017) -
Targeted short read sequencing and assembly of re-arrangements and candidate gene loci provide megabase diplotypes
por: Shin, GiWon, et al.
Publicado: (2019)