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A tightly regulated and adjustable CRISPR-dCas9 based AND gate in yeast
The robust and precise on and off switching of one or more genes of interest, followed by expression or repression is essential for many biological circuits as well as for industrial applications. However, many regulated systems published to date influence the viability of the host cell, show high b...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326796/ https://www.ncbi.nlm.nih.gov/pubmed/30476163 http://dx.doi.org/10.1093/nar/gky1191 |