Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment

The kinetochore is a proteinaceous complex that is essential for proper chromosome segregation. As a core member of the inner kinetochore, defects of each subunit in the CENP-H/I/K complex cause dysfunction of kinetochore that leads to chromosome mis-segregation and cell death. However, how the CENP...

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Detalles Bibliográficos
Autores principales: Hu, Liqiao, Huang, Hao, Hei, Mohan, Yang, Yang, Li, Sheng, Liu, Yunshan, Dou, Zhen, Wu, Mengying, Li, Jie, Wang, Guang-zhong, Yao, Xuebiao, Liu, Hong, He, Xiaojing, Tian, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326798/
https://www.ncbi.nlm.nih.gov/pubmed/30407575
http://dx.doi.org/10.1093/nar/gky1108

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