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Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication

Hepatitis C virus (HCV) infection is a major cause of human chronic liver disease and hepatocellular carcinoma. G-quadruplex (G4) is an important four-stranded secondary structure of nucleic acids. Recently, we discovered that the core gene of HCV contains a G4 RNA structure; however, the interactio...

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Detalles Bibliográficos
Autores principales: Bian, Wen-Xiu, Xie, Yan, Wang, Xiao-Ning, Xu, Guo-Hua, Fu, Bo-Shi, Li, Shu, Long, Gang, Zhou, Xiang, Zhang, Xiao-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326805/
https://www.ncbi.nlm.nih.gov/pubmed/30462330
http://dx.doi.org/10.1093/nar/gky1177

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