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Detection of epigenetic field defects using a weighted epigenetic distance-based method
Identifying epigenetic field defects, notably early DNA methylation alterations, is important for early cancer detection. Research has suggested these early methylation alterations are infrequent across samples and identifiable as outlier samples. Here we developed a weighted epigenetic distance-bas...
Autores principales: | Wang, Ya, Qian, Min, Ruan, Peifeng, Teschendorff, Andrew E, Wang, Shuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326818/ https://www.ncbi.nlm.nih.gov/pubmed/30304472 http://dx.doi.org/10.1093/nar/gky882 |
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