Data on migration of the non-invasive breast cancer cell line, MCF-7 treated with Bevacizumab using Real Time Cell Analyzer (RTCA)

Bevacizumab or Avastin® (Av), the recombinant antibody targeting VEGF, improves progression-free but not overall survival of metastatic breast cancer patients due to development of Av resistance. We showed that Av-therapy-induced inflammatory microenvironment contributes to the refractoriness to Av...

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Autores principales: EL-Hajjar, Layal, Shaito, Abdullah, Jalaleddine, Nour, Zibara, Kazem, Kazan, Jalal M., El-Saghir, Jamal, El-Sabban, Marwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327074/
https://www.ncbi.nlm.nih.gov/pubmed/30671510
http://dx.doi.org/10.1016/j.dib.2018.12.059
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author EL-Hajjar, Layal
Shaito, Abdullah
Jalaleddine, Nour
Zibara, Kazem
Kazan, Jalal M.
El-Saghir, Jamal
El-Sabban, Marwan
author_facet EL-Hajjar, Layal
Shaito, Abdullah
Jalaleddine, Nour
Zibara, Kazem
Kazan, Jalal M.
El-Saghir, Jamal
El-Sabban, Marwan
author_sort EL-Hajjar, Layal
collection PubMed
description Bevacizumab or Avastin® (Av), the recombinant antibody targeting VEGF, improves progression-free but not overall survival of metastatic breast cancer patients due to development of Av resistance. We showed that Av-therapy-induced inflammatory microenvironment contributes to the refractoriness to Av treatment. Here we present data regarding the effect of Av treatment on migration of a non-invasive breast cancer cell line, MCF-7. The data presented hereis related to the research article “Bevacizumab induces inflammation in MDA-MB-231 breast cancer cell line and in a mouse model” (Hajjar et al., 2018).
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spelling pubmed-63270742019-01-22 Data on migration of the non-invasive breast cancer cell line, MCF-7 treated with Bevacizumab using Real Time Cell Analyzer (RTCA) EL-Hajjar, Layal Shaito, Abdullah Jalaleddine, Nour Zibara, Kazem Kazan, Jalal M. El-Saghir, Jamal El-Sabban, Marwan Data Brief Biochemistry, Genetics and Molecular Biology Bevacizumab or Avastin® (Av), the recombinant antibody targeting VEGF, improves progression-free but not overall survival of metastatic breast cancer patients due to development of Av resistance. We showed that Av-therapy-induced inflammatory microenvironment contributes to the refractoriness to Av treatment. Here we present data regarding the effect of Av treatment on migration of a non-invasive breast cancer cell line, MCF-7. The data presented hereis related to the research article “Bevacizumab induces inflammation in MDA-MB-231 breast cancer cell line and in a mouse model” (Hajjar et al., 2018). Elsevier 2018-12-21 /pmc/articles/PMC6327074/ /pubmed/30671510 http://dx.doi.org/10.1016/j.dib.2018.12.059 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Biochemistry, Genetics and Molecular Biology
EL-Hajjar, Layal
Shaito, Abdullah
Jalaleddine, Nour
Zibara, Kazem
Kazan, Jalal M.
El-Saghir, Jamal
El-Sabban, Marwan
Data on migration of the non-invasive breast cancer cell line, MCF-7 treated with Bevacizumab using Real Time Cell Analyzer (RTCA)
title Data on migration of the non-invasive breast cancer cell line, MCF-7 treated with Bevacizumab using Real Time Cell Analyzer (RTCA)
title_full Data on migration of the non-invasive breast cancer cell line, MCF-7 treated with Bevacizumab using Real Time Cell Analyzer (RTCA)
title_fullStr Data on migration of the non-invasive breast cancer cell line, MCF-7 treated with Bevacizumab using Real Time Cell Analyzer (RTCA)
title_full_unstemmed Data on migration of the non-invasive breast cancer cell line, MCF-7 treated with Bevacizumab using Real Time Cell Analyzer (RTCA)
title_short Data on migration of the non-invasive breast cancer cell line, MCF-7 treated with Bevacizumab using Real Time Cell Analyzer (RTCA)
title_sort data on migration of the non-invasive breast cancer cell line, mcf-7 treated with bevacizumab using real time cell analyzer (rtca)
topic Biochemistry, Genetics and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327074/
https://www.ncbi.nlm.nih.gov/pubmed/30671510
http://dx.doi.org/10.1016/j.dib.2018.12.059
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