Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress

The transmembrane protein neuropilin-1 (NRP1) promotes vascular endothelial growth factor (VEGF) and extracellular matrix signaling in endothelial cells (ECs). Although it is established that NRP1 is essential for angiogenesis, little is known about its role in EC homeostasis. Here, we report that N...

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Detalles Bibliográficos
Autores principales: Issitt, Theo, Bosseboeuf, Emy, De Winter, Natasha, Dufton, Neil, Gestri, Gaia, Senatore, Valentina, Chikh, Anissa, Randi, Anna M., Raimondi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327076/
https://www.ncbi.nlm.nih.gov/pubmed/30623799
http://dx.doi.org/10.1016/j.isci.2018.12.005

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