Single-cell microRNA-mRNA co-sequencing reveals non-genetic heterogeneity and mechanisms of microRNA regulation

Measuring multiple omics profiles from the same single cell opens up the opportunity to decode molecular regulation that underlies intercellular heterogeneity in development and disease. Here, we present co-sequencing of microRNAs and mRNAs in the same single cell using a half-cell genomics approach...

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Detalles Bibliográficos
Autores principales: Wang, Nayi, Zheng, Ji, Chen, Zhuo, Liu, Yang, Dura, Burak, Kwak, Minsuk, Xavier-Ferrucio, Juliana, Lu, Yi-Chien, Zhang, Miaomiao, Roden, Christine, Cheng, Jijun, Krause, Diane S., Ding, Ye, Fan, Rong, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327095/
https://www.ncbi.nlm.nih.gov/pubmed/30626865
http://dx.doi.org/10.1038/s41467-018-07981-6

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