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A Tet/Q Hybrid System for Robust and Versatile Control of Transgene Expression in C. elegans

Binary gene regulatory tools such as the Tetracycline (Tet)-controlled transcription system have revolutionized genetic research in multiple organisms, but their applications to the worm remain very limited. Here we report that the canonical Tet system is largely inactive in the worm but can be adap...

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Detalles Bibliográficos
Autores principales: Mao, Shaoshuai, Qi, Yingchuan, Zhu, Huanhu, Huang, Xinxin, Zou, Yan, Chi, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327101/
https://www.ncbi.nlm.nih.gov/pubmed/30634168
http://dx.doi.org/10.1016/j.isci.2018.12.023

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