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A Tet/Q Hybrid System for Robust and Versatile Control of Transgene Expression in C. elegans
Binary gene regulatory tools such as the Tetracycline (Tet)-controlled transcription system have revolutionized genetic research in multiple organisms, but their applications to the worm remain very limited. Here we report that the canonical Tet system is largely inactive in the worm but can be adap...
Autores principales: | Mao, Shaoshuai, Qi, Yingchuan, Zhu, Huanhu, Huang, Xinxin, Zou, Yan, Chi, Tian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327101/ https://www.ncbi.nlm.nih.gov/pubmed/30634168 http://dx.doi.org/10.1016/j.isci.2018.12.023 |
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