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CD8(+) Cytotoxic-T-Lymphocyte Breadth Could Facilitate Early Immune Detection of Immunodeficiency Virus-Derived Epitopes with Limited Expression Levels

Cytotoxic-T-lymphocyte (CTL) responses are important to control the replication of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV). Accumulating evidence suggests that the ability of a few immunodominant T-cell populations to detect and kill HIV/SIV-infected cells is impor...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Tetsuo, Yamamoto, Hiroyuki, Matano, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327104/
https://www.ncbi.nlm.nih.gov/pubmed/30626618
http://dx.doi.org/10.1128/mSphere.00381-18