Cargando…

Oleanolic Acid Ameliorates Aβ(25-35) Injection-induced Memory Deficit in Alzheimer’s Disease Model Rats by Maintaining Synaptic Plasticity

BACKGROUND: Abnormal amyloid β (Aβ) accumulation and deposition in the hippocampus is an essential process in Alzheimer’s disease (AD). OBJECTIVE: To investigate whether Oleanolic acid (OA) could improve memory deficit in AD model and its possible mechanism. METHODS: Forty-five SD rats were randomly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Kai, Sun, Weiming, Zhang, Linlin, Guo, Wei, Xu, Jiachun, Liu, Shuang, Zhou, Zhen, Zhang, Yulian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327117/ https://www.ncbi.nlm.nih.gov/pubmed/29793416 http://dx.doi.org/10.2174/1871527317666180525113109

Ejemplares similares

20(S)-protopanaxadiol and oleanolic acid ameliorate cognitive deficits in APP/PS1 transgenic mice by enhancing hippocampal neurogenesis
por: Lin, Kaili, et al.
Publicado: (2021)

Interneurons: Role in Maintaining and Restoring Synaptic Plasticity
por: Calcagnotto, Maria Elisa
Publicado: (2016)

Oleanolic acid ameliorates intestinal alterations associated with EAE
por: Gutierrez, Beatriz, et al.
Publicado: (2020)

Electroacupuncture Ameliorates Cognitive Deficit and Improves Hippocampal Synaptic Plasticity in Adult Rat with Neonatal Maternal Separation
por: Guo, Lili, et al.
Publicado: (2018)

Profound deficits in hippocampal synaptic plasticity after traumatic brain injury and seizure is ameliorated by prophylactic levetiracetam
por: Chen, Yuan-Hao, et al.
Publicado: (2018)

BACE1 partial deletion induces synaptic plasticity deficit in adult mice
por: Lombardo, Sylvia, et al.
Publicado: (2019)

The Minocycline Ameliorated the Synaptic Plasticity Impairment in Vascular Dementia
por: Sharifi, Mohammad Davood, et al.
Publicado: (2021)

Hippocampal ischemia causes deficits in local field potential and synaptic plasticity
por: Wang, Shaoli, et al.
Publicado: (2015)

The seed oil of Paeonia ludlowii ameliorates Aβ25‐35‐induced Alzheimer's disease in rats
por: Lu, Ya‐Zhou, et al.
Publicado: (2021)

β-Amyrin Ameliorates Alzheimer’s Disease-Like Aberrant Synaptic Plasticity in the Mouse Hippocampus
por: Park, Hye Jin, et al.
Publicado: (2020)

Oleanolic acid ameliorates high glucose-induced endothelial dysfunction via PPARδ activation
por: Zhang, Zihui, et al.
Publicado: (2017)

Physiological Plasticity Is Important for Maintaining Sugarcane Growth under Water Deficit
por: Marchiori, Paulo E. R., et al.
Publicado: (2017)

Commentary: The Flavonoid Baicalein Rescues Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer’s Disease
por: Chirumbolo, Salvatore, et al.
Publicado: (2016)

SNAP-25 isoforms differentially regulate synaptic transmission and long-term synaptic plasticity at central synapses
por: Irfan, Muhammad, et al.
Publicado: (2019)

PT575. Citalopram Ameliorates Synaptic Plasticity Deficits in Different Cognition-associated Brain Regions Induced by Social Isolation in Middle-Aged Rats
por: Gong, Wei-Gang
Publicado: (2016)

p85S6K sustains synaptic GluA1 to ameliorate cognitive deficits in Alzheimer’s disease
por: Li, Jia-Bing, et al.
Publicado: (2023)

Downregulation of caveolin-1 contributes to the synaptic plasticity deficit in the hippocampus of aged rats
por: Liu, Yang, et al.
Publicado: (2013)

Late onset deficits in synaptic plasticity in the valproic acid rat model of autism
por: Martin, Henry G. S., et al.
Publicado: (2014)

Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington’s Disease
por: Kim, Anya, et al.
Publicado: (2020)

Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons
por: Takahashi, Miyuki, et al.
Publicado: (2022)

Oleanolic acid ethanol monosolvate
por: Froelich, Anna, et al.
Publicado: (2010)

Effect of exercise on cognitive function and synaptic plasticity in Alzheimer's disease models: A systematic review and meta-analysis
por: Guo, Linlin, et al.
Publicado: (2023)

Editorial: Molecular mechanism of neuroimmune modulation and synaptic plasticity in acute and chronic pain
por: Zhang, Linlin, et al.
Publicado: (2023)

Paternal spatial training enhances offspring’s cognitive performance and synaptic plasticity in wild-type but not improve memory deficit in Alzheimer’s mice
por: Zhang, Shujuan, et al.
Publicado: (2017)

EGB761 ameliorates chronic cerebral hypoperfusion-induced cognitive dysfunction and synaptic plasticity impairment
por: Yao, Zhao-Hui, et al.
Publicado: (2021)

Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress
por: Govindarajulu, Manoj, et al.
Publicado: (2020)

Postnatal Choline Supplementation Rescues Deficits in Synaptic Plasticity Following Prenatal Ethanol Exposure
por: Grafe, Erin L., et al.
Publicado: (2022)

Attention Deficit-Hyperactivity Disorder (ADHD): From Abnormal Behavior to Impairment in Synaptic Plasticity
por: Ugarte, Gonzalo, et al.
Publicado: (2023)

Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37
por: Zhang, Xiaoqun, et al.
Publicado: (2020)

Citalopram Ameliorates Impairments in Spatial Memory and Synaptic Plasticity in Female 3xTgAD Mice
por: Wei, Zhang, et al.
Publicado: (2017)

SIRT1 Is Involved in the Neuroprotection of Pterostilbene Against Amyloid β 25–35-Induced Cognitive Deficits in Mice
por: Zhu, Lin, et al.
Publicado: (2022)

SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice
por: Liu, Yong, et al.
Publicado: (2019)

Long-term maintenance of synaptic plasticity by Fullerenol Ameliorates lead-induced-impaired learning and memory in vivo
por: Zha, Yingying, et al.
Publicado: (2022)

Five-mer peptides prevent short-term spatial memory deficits in Aβ25-35-induced Alzheimer’s model mouse by suppressing Aβ25-35 aggregation and resolving its aggregate form
por: Nakamura, Rina, et al.
Publicado: (2023)

Synaptic plasticity in schizophrenia pathophysiology
por: Zhang, Kexuan, et al.
Publicado: (2022)

Synaptic plasticity in schizophrenia pathophysiology
por: Zhang, Kexuan, et al.
Publicado: (2023)

Early hippocampal synaptic plasticity and episodic like-memory deficits in a transgenic mouse model of Alzheimer disease - involvment of corticosterone
por: Lanté, Fabien, et al.
Publicado: (2013)

Estradiol prevents olfactory dysfunction induced by A-β 25–35 injection in hippocampus
por: Bernal-Mondragón, Carlos, et al.
Publicado: (2013)

An Intracellular Threonine of Amyloid-β Precursor Protein Mediates Synaptic Plasticity Deficits and Memory Loss
por: Lombino, Franco, et al.
Publicado: (2013)

Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome
por: Hethorn, Whitney R, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_oml5esvr5e1g3qhskuce6rd1bv