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Beta-sheet assembly of Tau and neurodegeneration in Drosophila melanogaster
The assembly of Tau into abundant β-sheet-rich filaments characterizes human tauopathies. A pathological pathway leading from monomeric to filamentous Tau is believed to be at the heart of these diseases. However, in Drosophila models of Tauopathy, neurodegeneration has been observed in the absence...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327151/ https://www.ncbi.nlm.nih.gov/pubmed/30240946 http://dx.doi.org/10.1016/j.neurobiolaging.2018.07.022 |