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Microbatch under-oil salt screening of organic cations: single-crystal growth of active pharmaceutical ingredients

Multicomponent solid forms of active pharmaceutical ingredients represent a modern method of tuning their physicochemical properties. Typically, salts are the most commonly used multicomponent solid form in the pharmaceutical industry. More than 38% are formulated as organic cations. Salt screening...

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Detalles Bibliográficos
Autores principales: Babor, Martin, Nievergelt, Philipp P., Čejka, Jan, Zvoníček, Vít, Spingler, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327184/
https://www.ncbi.nlm.nih.gov/pubmed/30713712
http://dx.doi.org/10.1107/S2052252518017876