Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer

Alteration of epigenetic enzymes is associated with the pathophysiology of colon cancer with an overexpression of histone deacetylase 8 (HDAC8) enzyme in this tissue. Numerous reports suggest that targeting HDAC8 is a viable strategy for developing new anticancer drugs. Flavonols provide a rich sour...

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Detalles Bibliográficos
Autores principales: Biswas, Subhankar, Reddy, Neetinkumar D., Jayashree, B. S., Rao, C. Mallikarjuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327263/
https://www.ncbi.nlm.nih.gov/pubmed/30687400
http://dx.doi.org/10.1155/2018/4751806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327263/
https://www.ncbi.nlm.nih.gov/pubmed/30687400
http://dx.doi.org/10.1155/2018/4751806

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