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Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer

Alteration of epigenetic enzymes is associated with the pathophysiology of colon cancer with an overexpression of histone deacetylase 8 (HDAC8) enzyme in this tissue. Numerous reports suggest that targeting HDAC8 is a viable strategy for developing new anticancer drugs. Flavonols provide a rich sour...

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Detalles Bibliográficos
Autores principales:	Biswas, Subhankar, Reddy, Neetinkumar D., Jayashree, B. S., Rao, C. Mallikarjuna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327263/ https://www.ncbi.nlm.nih.gov/pubmed/30687400 http://dx.doi.org/10.1155/2018/4751806

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