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The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation

OBJECTIVE: Organic nitrates such as isosorbide-5-mononitrate (ISMN) and isosorbide dinitrate (ISDN) are used for the treatment of patients with chronic symptomatic stable coronary artery disease and chronic congestive heart failure. Limiting side effects of these nitrovasodilators include nitrate to...

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Detalles Bibliográficos
Autores principales:	Steven, Sebastian, Oelze, Matthias, Hausding, Michael, Roohani, Siyer, Kashani, Fatemeh, Kröller-Schön, Swenja, Helmstädter, Johanna, Jansen, Thomas, Baum, Christine, Iglarz, Marc, Schulz, Eberhard, Münzel, Thomas, Daiber, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327264/ https://www.ncbi.nlm.nih.gov/pubmed/30687454 http://dx.doi.org/10.1155/2018/7845629

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