Cargando…

Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes

BACKGROUND: To determine the range of pupil size that has the largest iris volume in normal eyes. METHODS: 31 healthy adult Chinese volunteers underwent swept-source anterior segment OCT examination in both eyes. Pilocarpine 1% was instilled in a randomly selected eye (eye with induced miosis (ME))...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shuning, Jiang, Jing, Yang, Yiquan, Wu, Gewei, Li, Shi-Ming, Thomas, Ravi, Wang, Ningli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327274/
https://www.ncbi.nlm.nih.gov/pubmed/30687548
http://dx.doi.org/10.1155/2018/8058951
_version_ 1783386438327336960
author Li, Shuning
Jiang, Jing
Yang, Yiquan
Wu, Gewei
Li, Shi-Ming
Thomas, Ravi
Wang, Ningli
author_facet Li, Shuning
Jiang, Jing
Yang, Yiquan
Wu, Gewei
Li, Shi-Ming
Thomas, Ravi
Wang, Ningli
author_sort Li, Shuning
collection PubMed
description BACKGROUND: To determine the range of pupil size that has the largest iris volume in normal eyes. METHODS: 31 healthy adult Chinese volunteers underwent swept-source anterior segment OCT examination in both eyes. Pilocarpine 1% was instilled in a randomly selected eye (eye with induced miosis (ME)) of each participant to obtain iris volume (IV) measurements over a range of pupil sizes. OCT was performed prior to and one hour after pilocarpine in both ME and fellow eye (FE). Iris volume (IV), anterior chamber volume (ACV), anterior chamber depth (ACD), and pupil size (PS) were recorded. A scatter plot was used to depict the association between each pupil size and IV. RESULTS: The pupillary sizes for which IV was recorded in ME and FE ranged from 1.161 mm to 6.665 mm. The mean IV increased with miosis in both ME and FE; in 13 eyes, IV decreased with a decrease in pupillary size. PS between 3.812 and 6.665 mm was associated with an increase in IV, while PS between 3.159 and 5.54 mm was associated with a decrease. The relationship between PS and IV was in the shape of a downward parabola and was modeled using a quadratic equation (y = −1.3121x(2) + 8.8429x + 16.423, R(2) = 0.26886). The largest IV occurred at PS between 3 and 4 mm. CONCLUSIONS: The relationship between PS and IV in this study was in the shape of a downward parabola. The largest IV was recorded at a pupillary size between 3 and 4 mm. This trial is registered with ChiCTR-ROC-17013572.
format Online
Article
Text
id pubmed-6327274
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-63272742019-01-27 Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes Li, Shuning Jiang, Jing Yang, Yiquan Wu, Gewei Li, Shi-Ming Thomas, Ravi Wang, Ningli J Ophthalmol Clinical Study BACKGROUND: To determine the range of pupil size that has the largest iris volume in normal eyes. METHODS: 31 healthy adult Chinese volunteers underwent swept-source anterior segment OCT examination in both eyes. Pilocarpine 1% was instilled in a randomly selected eye (eye with induced miosis (ME)) of each participant to obtain iris volume (IV) measurements over a range of pupil sizes. OCT was performed prior to and one hour after pilocarpine in both ME and fellow eye (FE). Iris volume (IV), anterior chamber volume (ACV), anterior chamber depth (ACD), and pupil size (PS) were recorded. A scatter plot was used to depict the association between each pupil size and IV. RESULTS: The pupillary sizes for which IV was recorded in ME and FE ranged from 1.161 mm to 6.665 mm. The mean IV increased with miosis in both ME and FE; in 13 eyes, IV decreased with a decrease in pupillary size. PS between 3.812 and 6.665 mm was associated with an increase in IV, while PS between 3.159 and 5.54 mm was associated with a decrease. The relationship between PS and IV was in the shape of a downward parabola and was modeled using a quadratic equation (y = −1.3121x(2) + 8.8429x + 16.423, R(2) = 0.26886). The largest IV occurred at PS between 3 and 4 mm. CONCLUSIONS: The relationship between PS and IV in this study was in the shape of a downward parabola. The largest IV was recorded at a pupillary size between 3 and 4 mm. This trial is registered with ChiCTR-ROC-17013572. Hindawi 2018-12-27 /pmc/articles/PMC6327274/ /pubmed/30687548 http://dx.doi.org/10.1155/2018/8058951 Text en Copyright © 2018 Shuning Li et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Li, Shuning
Jiang, Jing
Yang, Yiquan
Wu, Gewei
Li, Shi-Ming
Thomas, Ravi
Wang, Ningli
Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes
title Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes
title_full Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes
title_fullStr Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes
title_full_unstemmed Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes
title_short Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes
title_sort pupil size associated with the largest iris volume in normal chinese eyes
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327274/
https://www.ncbi.nlm.nih.gov/pubmed/30687548
http://dx.doi.org/10.1155/2018/8058951
work_keys_str_mv AT lishuning pupilsizeassociatedwiththelargestirisvolumeinnormalchineseeyes
AT jiangjing pupilsizeassociatedwiththelargestirisvolumeinnormalchineseeyes
AT yangyiquan pupilsizeassociatedwiththelargestirisvolumeinnormalchineseeyes
AT wugewei pupilsizeassociatedwiththelargestirisvolumeinnormalchineseeyes
AT lishiming pupilsizeassociatedwiththelargestirisvolumeinnormalchineseeyes
AT thomasravi pupilsizeassociatedwiththelargestirisvolumeinnormalchineseeyes
AT wangningli pupilsizeassociatedwiththelargestirisvolumeinnormalchineseeyes