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Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway

BACKGROUND: Acetaminophen (APAP) overdose-induced acute liver failure (ALF) is mainly resulted from uncontrolled oxidative stress. Nuclear factor-erythroid 2-related factor 2 (Nrf2), a key antioxidant transcription factor, is essential for alleviating APAP-induced hepatotoxicity. Corilagin (Cori) is...

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Detalles Bibliográficos
Autores principales:	Lv, Hongming, Hong, Lihua, Tian, Ye, Yin, Changjiu, Zhu, Chao, Feng, Haihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327405/ https://www.ncbi.nlm.nih.gov/pubmed/30630510 http://dx.doi.org/10.1186/s12964-018-0314-2

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