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Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes
BACKGROUND: Early life is a period of drastic epigenetic remodeling in which the epigenome is especially sensitive to extrinsic and intrinsic influence. However, the epigenome-wide dynamics of the DNA methylation changes that occur during this period have not been sufficiently characterized in longi...
Autores principales: | Pérez, Raúl F., Santamarina, Pablo, Tejedor, Juan Ramón, Urdinguio, Rocío G., Álvarez-Pitti, Julio, Redon, Pau, Fernández, Agustín F., Fraga, Mario F., Lurbe, Empar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327427/ https://www.ncbi.nlm.nih.gov/pubmed/30626398 http://dx.doi.org/10.1186/s12967-018-1751-9 |
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