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Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration
Alzheimer’s disease (AD) is pathologically characterized by the accumulation of amyloid-β (Aβ) plaques, neurofibrillary tangles and widespread neuronal loss in the brain. In recent years, blood biomarkers have emerged as a realistic prospect to highlight accumulating pathology for secondary preventi...
Autores principales: | Ashton, Nicholas J., Leuzy, Antoine, Lim, Yau Mun, Troakes, Claire, Hortobágyi, Tibor, Höglund, Kina, Aarsland, Dag, Lovestone, Simon, Schöll, Michael, Blennow, Kaj, Zetterberg, Henrik, Hye, Abdul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327431/ https://www.ncbi.nlm.nih.gov/pubmed/30626432 http://dx.doi.org/10.1186/s40478-018-0649-3 |
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