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A complex translocation (1;17;15) with spliced short-type PML-RARA fusion transcripts in acute promyelocytic leukemia: A case report

The promyelocytic leukemia (PML)-retinoic acid receptor α (RARA) fusion is hypothesized to serve a vital role in the pathogenesis of acute promyelocytic leukemia (APL), which results from a reciprocal translocation between chromosomes 15 and 17, t(15;17)(q24;q21). A minority of APL cases lack the cl...

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Detalles Bibliográficos
Autores principales: Lv, Lili, Yang, Longfei, Cui, Honghua, Ma, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327484/
https://www.ncbi.nlm.nih.gov/pubmed/30680014
http://dx.doi.org/10.3892/etm.2018.7091

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