An application of a pattern-mixture model with multiple imputation for the analysis of longitudinal trials with protocol deviations

BACKGROUND: The benefit of a given treatment can be evaluated via a randomized clinical trial design. However, protocol deviations may severely compromise treatment effect since such deviations often lead to missing values. The assumption that methods of analysis can account for the missing data can...

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Detalles Bibliográficos
Autores principales: Iddrisu, Abdul-Karim, Gumedze, Freedom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327569/
https://www.ncbi.nlm.nih.gov/pubmed/30626328
http://dx.doi.org/10.1186/s12874-018-0639-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327569/
https://www.ncbi.nlm.nih.gov/pubmed/30626328
http://dx.doi.org/10.1186/s12874-018-0639-y

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