Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India

Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clini...

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Detalles Bibliográficos
Autores principales: Mehta, Swati Pabbi, Tiwari, Aseem Kumar, Puri, Rajesh, Arora, Dinesh, Aggarwal, Geet, Ratan, Ankita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327775/
https://www.ncbi.nlm.nih.gov/pubmed/30692801
http://dx.doi.org/10.4103/ajts.AJTS_86_17
Descripción
Sumario:Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. He was treated with TPE along with intravenous insulin, statins, and fibrates. TPE resulted in immediate relief of symptoms as well as a marked improvement in laboratory values, with 74.5% reduction in triglycerides after a single session. TPE can be successfully utilized as an adjunct in HTG-induced pancreatitis.

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