Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India

Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clini...

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Autores principales: Mehta, Swati Pabbi, Tiwari, Aseem Kumar, Puri, Rajesh, Arora, Dinesh, Aggarwal, Geet, Ratan, Ankita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327775/
https://www.ncbi.nlm.nih.gov/pubmed/30692801
http://dx.doi.org/10.4103/ajts.AJTS_86_17
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author Mehta, Swati Pabbi
Tiwari, Aseem Kumar
Puri, Rajesh
Arora, Dinesh
Aggarwal, Geet
Ratan, Ankita
author_facet Mehta, Swati Pabbi
Tiwari, Aseem Kumar
Puri, Rajesh
Arora, Dinesh
Aggarwal, Geet
Ratan, Ankita
author_sort Mehta, Swati Pabbi
collection PubMed
description Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. He was treated with TPE along with intravenous insulin, statins, and fibrates. TPE resulted in immediate relief of symptoms as well as a marked improvement in laboratory values, with 74.5% reduction in triglycerides after a single session. TPE can be successfully utilized as an adjunct in HTG-induced pancreatitis.
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spelling pubmed-63277752019-01-28 Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India Mehta, Swati Pabbi Tiwari, Aseem Kumar Puri, Rajesh Arora, Dinesh Aggarwal, Geet Ratan, Ankita Asian J Transfus Sci Case Report Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. He was treated with TPE along with intravenous insulin, statins, and fibrates. TPE resulted in immediate relief of symptoms as well as a marked improvement in laboratory values, with 74.5% reduction in triglycerides after a single session. TPE can be successfully utilized as an adjunct in HTG-induced pancreatitis. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6327775/ /pubmed/30692801 http://dx.doi.org/10.4103/ajts.AJTS_86_17 Text en Copyright: © 2018 Asian Journal of Transfusion Science http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Mehta, Swati Pabbi
Tiwari, Aseem Kumar
Puri, Rajesh
Arora, Dinesh
Aggarwal, Geet
Ratan, Ankita
Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India
title Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India
title_full Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India
title_fullStr Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India
title_full_unstemmed Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India
title_short Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India
title_sort severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: report from india
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327775/
https://www.ncbi.nlm.nih.gov/pubmed/30692801
http://dx.doi.org/10.4103/ajts.AJTS_86_17
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