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Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway

BACKGROUND: Palbociclib, a specific inhibitor of CDK4/6, has been shown to provide a survival benefit in hormone receptor-positive advanced breast cancer; however, its resistance and related mechanisms are unclear. MATERIAL/METHODS: In this study, we constructed palbociclib-resistant hormone recepto...

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Detalles Bibliográficos
Autores principales:	Chen, Lin, Yang, Guangsheng, Dong, Hongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327776/ https://www.ncbi.nlm.nih.gov/pubmed/30605443 http://dx.doi.org/10.12659/MSM.912929

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