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Distraction Osteogenesis After Stem Cell Transplantation: A Pioneer Approach

Allogeneic hematopoietic stem cell transplantation (HSCT) is an established therapy and is without alternative for certain groups of patients. Successful HSCT induces both long-lasting remission and tolerance without the need for further immunosuppression. In this case, cellular repair and regenerat...

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Detalles Bibliográficos
Autores principales: Voss, Jan Oliver, Kühl, Jörg-Sven, Holm, Maike, Hauptmann, Kathrin, Adolphs, Nicolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327817/
https://www.ncbi.nlm.nih.gov/pubmed/30693250
http://dx.doi.org/10.4103/ams.ams_41_18
Descripción
Sumario:Allogeneic hematopoietic stem cell transplantation (HSCT) is an established therapy and is without alternative for certain groups of patients. Successful HSCT induces both long-lasting remission and tolerance without the need for further immunosuppression. In this case, cellular repair and regenerative processes work in a physiologic manner allowing elective surgical procedures, such as the interdisciplinary correction of dentofacial anomalies. Here, we report the successful management of transverse maxillary deficiency by transpalatal distraction and subsequent orthodontic treatment in a 12-year-old boy who underwent HSCT for high-risk acute lymphoblastic leukemia at 5 years of age.