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Genetic and phenotypic difference in CD8(+) T cell exhaustion between chronic hepatitis B infection and hepatocellular carcinoma

BACKGROUND: Several recent studies published have suggested that T cell exhaustion exists both in chronic infection and cancer. However, to date, few studies have investigated their differences. Here we designed this study to explore the genetic and phenotypic difference in CD8(+) T cell exhaustion...

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Detalles Bibliográficos
Autores principales: Wang, Xiaochen, He, Qifeng, Shen, Haiyuan, Lu, Xiao-Jie, Sun, Beicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327916/
https://www.ncbi.nlm.nih.gov/pubmed/29666149
http://dx.doi.org/10.1136/jmedgenet-2018-105267

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