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Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies

Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE) inhibitors are interesting compounds for different therapeutic applications, among which Alzheimer’s disease. Here, we investigated the inhibition of these cholinesterases with uracil derivatives. The mechanism of inhibition of these enzy...

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Detalles Bibliográficos
Autores principales:	Cavdar, Huseyin, Senturk, Murat, Guney, Murat, Durdagi, Serdar, Kayik, Gulru, Supuran, Claudiu T., Ekinci, Deniz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327988/ https://www.ncbi.nlm.nih.gov/pubmed/30734597 http://dx.doi.org/10.1080/14756366.2018.1543288

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