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A comprehensive review on tyrosinase inhibitors

Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. Therefore, its inhibitors can be attractive in cosmetics and medicinal industries as depigmentation agents and also in food and agriculture...

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Detalles Bibliográficos
Autores principales: Zolghadri, Samaneh, Bahrami, Asieh, Hassan Khan, Mahmud Tareq, Munoz-Munoz, J., Garcia-Molina, F., Garcia-Canovas, F., Saboury, Ali Akbar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327992/
https://www.ncbi.nlm.nih.gov/pubmed/30734608
http://dx.doi.org/10.1080/14756366.2018.1545767
Descripción
Sumario:Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. Therefore, its inhibitors can be attractive in cosmetics and medicinal industries as depigmentation agents and also in food and agriculture industries as antibrowning compounds. For this purpose, many natural, semi-synthetic and synthetic inhibitors have been developed by different screening methods to date. This review has focused on the tyrosinase inhibitors discovered from all sources and biochemically characterised in the last four decades.