Cargando…

A feature-based analysis identifies COL1A2 as a regulator in pancreatic cancer

This study aimed to identify genetic biomarkers in pancreatic cancer (PC) and explore its function in PC via a feature-base analysis of bioinformatics. OMIM and DisGeNET databases discovered 209 PC connected genes and then 516 connected genes were identified. We selected 29 genes according to optima...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Jie, Liu, Jing, Wei, XiaoQing, Yu, Qi, Niu, XiangHuan, Tang, ShuHong, Song, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327995/ https://www.ncbi.nlm.nih.gov/pubmed/30734598 http://dx.doi.org/10.1080/14756366.2018.1484734

Ejemplares similares

Main features of COL4A1-COL4A2 related cerebral microangiopathies
por: Guey, Stéphanie, et al.
Publicado: (2022)

Integrated Analysis of ECT2 and COL17A1 as Potential Biomarkers for Pancreatic Cancer
por: Huang, Wen-liang, et al.
Publicado: (2022)

Prognostic value of COL6A3 in pancreatic adenocarcinoma
por: Svoronos, Christos, et al.
Publicado: (2020)

Radiation increases COL1A1, COL3A1, and COL1A2 expression in breast cancer
por: Yao, Guorong, et al.
Publicado: (2022)

Collagen fiber features and COL1A1: are they associated with elastic parameters in breast lesions, and can COL1A1 predict axillary lymph node metastasis?
por: Jiang, Ying, et al.
Publicado: (2022)

Novel mutations in COL4A3, COL4A4, and COL4A5 in Chinese patients with Alport Syndrome
por: Liu, Jian-Hong, et al.
Publicado: (2017)

Differential Expression of COL1A1, COL1A2, COL6A3, and SULF1 as Prognostic Biomarkers in Gastric Cancer
por: Hu, Yan, et al.
Publicado: (2021)

COL3A1, COL5A1 and COL6A2 serve as potential molecular biomarkers for osteoarthritis based on weighted gene co‑expression network analysis bioinformatics analysis
por: Zhang, Yufeng, et al.
Publicado: (2023)

Prenatal Cases Reflect the Complexity of the COL1A1/2 Associated Osteogenesis Imperfecta
por: Yang, Kai, et al.
Publicado: (2022)

Case report: Recurrent pontine stroke and leukoencephalopathy in a patient with de novo mutation in COL4A1
por: Zhang, Hui, et al.
Publicado: (2023)

Effect of heterozygous pathogenic COL4A3 or COL4A4 variants on patients with X‐linked Alport syndrome
por: Zhang, Yanqin, et al.
Publicado: (2019)

COL6A1 promotes metastasis and predicts poor prognosis in patients with pancreatic cancer
por: Owusu-Ansah, Kwabena Gyabaah, et al.
Publicado: (2019)

Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction
por: Yang, Wei, et al.
Publicado: (2016)

Role of COL6A3 in colorectal cancer
por: Liu, Wei, et al.
Publicado: (2018)

USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation
por: Wu, Xiaosheng, et al.
Publicado: (2021)

Clinical value and potential mechanisms of COL8A1 upregulation in breast cancer: a comprehensive analysis
por: Peng, Wei, et al.
Publicado: (2020)

Presumed COL4A3/COL4A4 Missense/Synonymous Variants Induce Aberrant Splicing
por: Deng, Haiyue, et al.
Publicado: (2022)

Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis
por: Yuan, Lushun, et al.
Publicado: (2017)

Multi-level transcriptome sequencing identifies COL1A1 as a candidate marker in human heart failure progression
por: Hua, Xiumeng, et al.
Publicado: (2020)

Stroma derived COL6A3 is a potential prognosis marker of colorectal carcinoma revealed by quantitative proteomics
por: Qiao, Jie, et al.
Publicado: (2015)

Abnormal mRNA Splicing Effect of COL4A3 to COL4A5 Unclassified Variants
por: Zhang, Yanqin, et al.
Publicado: (2023)

Effect of Glucose Variability on Pancreatic Cancer Through Regulation of COL6A1
por: Yu, Qian, et al.
Publicado: (2021)

COL10A1 promotes tumorigenesis by modulating CD276 in pancreatic adenocarcinoma
por: Xu, Qiaodong, et al.
Publicado: (2023)

Atopic Eczema: Genetic Analysis of COL6A5, COL8A1, and COL10A1 in Mediterranean Populations
por: Strafella, Claudia, et al.
Publicado: (2019)

COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation
por: Song, Yao, et al.
Publicado: (2023)

Comprehensive Analysis Identifies COL1A1, COL3A1, and POSTN as Key Genes Associated with Brain Metastasis in Patients with Breast Cancer
por: Wu, Weidan, et al.
Publicado: (2022)

A novel COL1A1 variant in a family with clinical features of hypermobile Ehlers‐Danlos syndrome that proved to be a COL1‐related overlap disorder
por: Foy, Malika, et al.
Publicado: (2021)

Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1
por: Urbizu, Aintzane, et al.
Publicado: (2021)

Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics analysis
por: Ding, Jingyi, et al.
Publicado: (2020)

Mutation survey and genotype-phenotype analysis of COL2A1 and COL11A1 genes in 16 Chinese patients with Stickler syndrome
por: Wang, Xun, et al.
Publicado: (2016)

The Associations of Single Nucleotide Polymorphisms of the COL3A1, COL6A5, and COL8A1 Genes with Atopic Dermatitis
por: Szalus, Krzysztof, et al.
Publicado: (2023)

Prevalence of clinical, pathological and molecular features of glomerular basement membrane nephropathy caused by COL4A3 or COL4A4 mutations: a systematic review
por: Matthaiou, Andreas, et al.
Publicado: (2020)

COL3A1, CXCL8, VCAN, THBS2, and COL1A2 are correlated with the onset of biliary atresia
por: Li, Hui, et al.
Publicado: (2023)

Clinical Manifestations of Alport Syndrome-Diffuse Leiomyomatosis Patients With Contiguous Gene Deletions in COL4A6 and COL4A5
por: Zhou, Xi, et al.
Publicado: (2021)

Molecular Characteristics and Promoter Analysis of Porcine COL1A1
por: Xiang, Guangming, et al.
Publicado: (2022)

Retracted: Comprehensive Analysis Identifies COL1A1, COL3A1, and POSTN as Key Genes Associated with Brain Metastasis in Patients with Breast Cancer
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Bioinformatics Analysis and Experimental Verification Identify Downregulation of COL27A1 in Poor Segmental Congenital Scoliosis
por: Hu, Zongshan, et al.
Publicado: (2022)

Polymorphisms in COL4A3 and COL4A4 genes associated with keratoconus
por: Štabuc-Šilih, Mirna, et al.
Publicado: (2009)

The correlation and role analysis of COL4A1 and COL4A2 in hepatocarcinogenesis
por: Liu, Yanli, et al.
Publicado: (2020)

Clinical significance of COL1A1 and COL1A2 expression levels in hypopharyngeal squamous cell carcinoma
por: Lin, Peiliang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4u8vm38k96i42s8qajalegt7ab