Cargando…

Hydroxyl-substituted double Schiff-base condensed 4-piperidone/cyclohexanones as potential anticancer agents with biological evaluation

Novel hydroxyl-substituted double Schiff-base 4-piperidone/cyclohexanone derivatives, 3a–e, 4a–e, 5a–d, and 6a–c, were synthesized and fully characterized by (1)H NMR, IR and elemental analysis. The cytotoxicity against human carcinoma cell lines A549, SGC7901, HePG2, HeLa, K562, THP-1 and non-malig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lianshuang, Chen, Qin, Hou, Guige, Zhao, Wei, Hou, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327999/ https://www.ncbi.nlm.nih.gov/pubmed/30734613 http://dx.doi.org/10.1080/14756366.2018.1501042

Ejemplares similares

A Twist on Facial Selectivity of Hydride Reductions of Cyclic Ketones: Twist-Boat Conformers in Cyclohexanone, Piperidone, and Tropinone Reactions
por: Neufeldt, Sharon R., et al.
Publicado: (2014)

Trifluoromethyl-substituted 3,5-bis(arylidene)-4-piperidones as potential anti-hepatoma and anti-inflammation agents by inhibiting NF-кB activation
por: Cong, Wei, et al.
Publicado: (2021)

Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents
por: Al-Majid, Abdullah Mohammed, et al.
Publicado: (2021)

Highly selective self-condensation of cyclohexanone: the distinct catalytic behaviour of HRF5015
por: Peng, Xiujing, et al.
Publicado: (2020)

Spectroscopic and Theoretical Studies of Some 3-(4′-Substituted phenylsulfanyl)-1-methyl-2-piperidones
por: Olivato, Paulo R., et al.
Publicado: (2013)

Study of the Electrochemical Behavior of N-Substituted-4-Piperidones Curcumin Analogs: A Combined Experimental and Theoretical Approach
por: Amalraj, John, et al.
Publicado: (2022)

MOF-808 as a Highly Active Catalyst for the Diastereoselective Reduction of Substituted Cyclohexanones
por: Mautschke, Hans Hilmar, et al.
Publicado: (2022)

1-Methyl-3-phenylsulfonyl-2-piperidone
por: Zukerman-Schpector, Julio, et al.
Publicado: (2008)

Regio and stereoselective synthesis of anticancer spirooxindolopyrrolidine embedded piperidone heterocyclic hybrids derived from one-pot cascade protocol
por: Arumugam, Natarajan, et al.
Publicado: (2018)

Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and α-Glucosidase Inhibitory Activities and In Silico Study
por: Al-Majid, Abdullah Mohammed, et al.
Publicado: (2019)

1-Benzoyl-3-methyl-2,6-diphenyl-4-piperidone
por: Nithya, P., et al.
Publicado: (2009)

Synthesis and bio-properties of 4-piperidone containing compounds as curcumin mimics
por: Girgis, Adel S., et al.
Publicado: (2022)

Bioactive Salen-type Schiff Base Transition Metal Complexes as Possible Anticancer Agents
por: Damercheli, Maryam, et al.
Publicado: (2019)

Associative behavior of polyimide/cyclohexanone solutions
por: Chen, Hongxiang, et al.
Publicado: (2019)

1-Benzyl-3,5-bis(2-thienylmethylene)-4-piperidone
por: Sun, Ju-feng, et al.
Publicado: (2009)

3,5-Bis(arylidene)-4-piperidones as potential dengue protease inhibitors
por: Osman, Hasnah, et al.
Publicado: (2017)

Novel Biologically Active N-Substituted Benzimidazole Derived Schiff Bases: Design, Synthesis, and Biological Evaluation
por: Beč, Anja, et al.
Publicado: (2023)

Reaction-activated palladium catalyst for dehydrogenation of substituted cyclohexanones to phenols and H(2) without oxidants and hydrogen acceptors
por: Zhang, Jingwu, et al.
Publicado: (2015)

Cyclohexanone-Based Chalcones as Alternatives for Fuel Additives
por: Sallum, Lóide O., et al.
Publicado: (2022)

Synthesis and Biological Evaluation of Novel 6-Hydroxy-benzo[d][1,3]oxathiol-2-one Schiff Bases as Potential Anticancer Agents
por: Chazin, Eliza de Lucas, et al.
Publicado: (2015)

Investigation of the role of stereoelectronic effects in the conformation of piperidones by NMR spectroscopy and X-ray diffraction
por: Garcias-Morales, Cesar, et al.
Publicado: (2015)

Synthetic Approaches for Piperidone-Based Templates as Scaffolds to Access Chirally Enriched Donepezil Analogues
por: Poeschl, Anna, et al.
Publicado: (2020)

Biological investigation of novel metal complexes of 2-amino-4-substituted phenylthiazole Schiff bases
por: Sahoo, Jyotirmaya, et al.
Publicado: (2017)

Synthesis of potentially new schiff bases of N-substituted-2-quinolonylacetohydrazides as anti-COVID-19 agents
por: Alshammari, Mohammed B., et al.
Publicado: (2021)

Asymmetric Baeyer–Villiger oxidation: classical and parallel kinetic resolution of 3-substituted cyclohexanones and desymmetrization of meso-disubstituted cycloketones
por: Wu, Wangbin, et al.
Publicado: (2019)

The Molecular Targets and Anti-Invasive Effects of 2,6-bis-(4-hydroxyl-3methoxybenzylidine) cyclohexanone or BHMC in MDA-MB-231 Human Breast Cancer Cells
por: Harun, Siti Nor Aini, et al.
Publicado: (2018)

t - $\overline{t}$ condensates as Higgs substitutes
por: Lindner, Manfred
Publicado: (1991)

Synthesis and Biological Evaluation of Novel Alkyl Amine Substituted Icariside II Derivatives as Potential Anticancer Agents
por: Wu, Tong, et al.
Publicado: (2018)

Synthesis and Biological Evaluation of 4β-N-Acetylamino Substituted Podophyllotoxin Derivatives as Novel Anticancer Agents
por: Wei, Jinbao, et al.
Publicado: (2019)

Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity
por: Chhikara, Aruna, et al.
Publicado: (2022)

Cyclohexanone 2-nitrophenylhydrazone
por: Yang, Bao-he, et al.
Publicado: (2010)

Calorimetric and Computational Study of Enthalpy of Formation of Diperoxide of Cyclohexanone
por: Romero, Jorge Marcelo, et al.
Publicado: (2007)

Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase
por: Romero, Elvira, et al.
Publicado: (2016)

Stabilization of cyclohexanone monooxygenase by computational and experimental library design
por: Fürst, Maximilian J. L. J., et al.
Publicado: (2019)

Dual catalytic enantioselective desymmetrization of allene-tethered cyclohexanones
por: Zhang, Lin, et al.
Publicado: (2020)

Synthesis of Substituted Oxo-Azepines by Regio- and Diastereoselective Hydroxylation
por: Spedding, Harold, et al.
Publicado: (2017)

Synthesis of N-Substituted 5-Iodouracils as Antimicrobial and Anticancer Agents
por: Prachayasittikul, Supaluk, et al.
Publicado: (2009)

14-Substituted Diquinothiazines as a New Group of Anticancer Agents
por: Jeleń, Małgorzata, et al.
Publicado: (2023)

A Synthetic Curcuminoid Analogue, 2,6-Bis-4-(Hydroxyl-3-Methoxybenzylidine)-Cyclohexanone (BHMC) Ameliorates Acute Airway Inflammation of Allergic Asthma in Ovalbumin-Sensitized Mice
por: Tham, Chau Ling, et al.
Publicado: (2021)

Synthesis and characterization of different complexes derived from Schiff base and evaluation as a potential anticancer, antimicrobial, and insecticide agent
por: Aroua, Lotfi M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4nvk7p0pcs1ke315lh356usi4j