Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer

Pancreatic ductal adenocarcinoma (PDAC) has the worst prognosis among solid malignancies and improved therapeutic strategies are needed to improve outcomes. Patient-derived xenografts (PDX) and patient-derived organoids (PDO) serve as promising tools to identify new drugs with therapeutic potential...

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Detalles Bibliográficos
Autores principales: Gendoo, Deena M. A., Denroche, Robert E., Zhang, Amy, Radulovich, Nikolina, Jang, Gun Ho, Lemire, Mathieu, Fischer, Sandra, Chadwick, Dianne, Lungu, Ilinca M., Ibrahimov, Emin, Cao, Ping-Jiang, Stein, Lincoln D., Wilson, Julie M., Bartlett, John M. S., Tsao, Ming-Sound, Dhani, Neesha, Hedley, David, Gallinger, Steven, Haibe-Kains, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328084/
https://www.ncbi.nlm.nih.gov/pubmed/30629588
http://dx.doi.org/10.1371/journal.pcbi.1006596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328084/
https://www.ncbi.nlm.nih.gov/pubmed/30629588
http://dx.doi.org/10.1371/journal.pcbi.1006596

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