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Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells
Melatonin has protective roles in normal cells and cytotoxic actions in cancer cells, with effects involving autophagy and nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor pathways. Hypoxia/reoxygenation (H/R) induces oxidative damage and apoptosis. These consequences activate...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328125/ https://www.ncbi.nlm.nih.gov/pubmed/30629581 http://dx.doi.org/10.1371/journal.pone.0202458 |