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A meta-analysis of randomized controlled trials that compare standard doxorubicin with other first-line chemotherapies for advanced/metastatic soft tissue sarcomas

OBJECTIVE: The standard treatment for patients with advanced/metastatic soft tissue sarcomas (ASTS) is systemic chemotherapy with doxorubicin. A previous meta-analysis of 8 randomized controlled trials (RCTs) demonstrated the superiority of single-agent doxorubicin over doxorubicin-based combination...

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Detalles Bibliográficos
Autores principales: Tanaka, Kazuhiro, Kawano, Masanori, Iwasaki, Tatsuya, Itonaga, Ichiro, Tsumura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328231/
https://www.ncbi.nlm.nih.gov/pubmed/30629708
http://dx.doi.org/10.1371/journal.pone.0210671