Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis

ABSTRACT: Isoselagintamarlin A (1), a selaginellin analogue featured a rare benzofuran unit, was isolated from Selaginella tamariscina. Its complete structural assignment was established through a combination of high-field NMR technique and biomimetic synthesis. Notably, isoselagintamarlin A (1) was...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Qin-Feng, Shao, Li-Dong, Wu, Xing-De, Liu, Jiang-Xin, Zhao, Qin-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328423/
https://www.ncbi.nlm.nih.gov/pubmed/30607860
http://dx.doi.org/10.1007/s13659-018-0195-5
Descripción
Sumario:ABSTRACT: Isoselagintamarlin A (1), a selaginellin analogue featured a rare benzofuran unit, was isolated from Selaginella tamariscina. Its complete structural assignment was established through a combination of high-field NMR technique and biomimetic synthesis. Notably, isoselagintamarlin A (1) was successfully synthesized via sequential oxidations and intramolecular cyclization. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13659-018-0195-5) contains supplementary material, which is available to authorized users.

Ejemplares similares