Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis

ABSTRACT: Isoselagintamarlin A (1), a selaginellin analogue featured a rare benzofuran unit, was isolated from Selaginella tamariscina. Its complete structural assignment was established through a combination of high-field NMR technique and biomimetic synthesis. Notably, isoselagintamarlin A (1) was...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Qin-Feng, Shao, Li-Dong, Wu, Xing-De, Liu, Jiang-Xin, Zhao, Qin-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328423/
https://www.ncbi.nlm.nih.gov/pubmed/30607860
http://dx.doi.org/10.1007/s13659-018-0195-5
_version_ 1783386637222281216
author Zhu, Qin-Feng
Shao, Li-Dong
Wu, Xing-De
Liu, Jiang-Xin
Zhao, Qin-Shi
author_facet Zhu, Qin-Feng
Shao, Li-Dong
Wu, Xing-De
Liu, Jiang-Xin
Zhao, Qin-Shi
author_sort Zhu, Qin-Feng
collection PubMed
description ABSTRACT: Isoselagintamarlin A (1), a selaginellin analogue featured a rare benzofuran unit, was isolated from Selaginella tamariscina. Its complete structural assignment was established through a combination of high-field NMR technique and biomimetic synthesis. Notably, isoselagintamarlin A (1) was successfully synthesized via sequential oxidations and intramolecular cyclization. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13659-018-0195-5) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-6328423
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Springer Singapore
record_format MEDLINE/PubMed
spelling pubmed-63284232019-01-25 Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis Zhu, Qin-Feng Shao, Li-Dong Wu, Xing-De Liu, Jiang-Xin Zhao, Qin-Shi Nat Prod Bioprospect Original Article ABSTRACT: Isoselagintamarlin A (1), a selaginellin analogue featured a rare benzofuran unit, was isolated from Selaginella tamariscina. Its complete structural assignment was established through a combination of high-field NMR technique and biomimetic synthesis. Notably, isoselagintamarlin A (1) was successfully synthesized via sequential oxidations and intramolecular cyclization. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13659-018-0195-5) contains supplementary material, which is available to authorized users. Springer Singapore 2019-01-03 /pmc/articles/PMC6328423/ /pubmed/30607860 http://dx.doi.org/10.1007/s13659-018-0195-5 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Zhu, Qin-Feng
Shao, Li-Dong
Wu, Xing-De
Liu, Jiang-Xin
Zhao, Qin-Shi
Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis
title Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis
title_full Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis
title_fullStr Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis
title_full_unstemmed Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis
title_short Isolation, Structural Assignment of Isoselagintamarlin A from Selaginella tamariscina and Its Biomimetic Synthesis
title_sort isolation, structural assignment of isoselagintamarlin a from selaginella tamariscina and its biomimetic synthesis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328423/
https://www.ncbi.nlm.nih.gov/pubmed/30607860
http://dx.doi.org/10.1007/s13659-018-0195-5
work_keys_str_mv AT zhuqinfeng isolationstructuralassignmentofisoselagintamarlinafromselaginellatamariscinaanditsbiomimeticsynthesis
AT shaolidong isolationstructuralassignmentofisoselagintamarlinafromselaginellatamariscinaanditsbiomimeticsynthesis
AT wuxingde isolationstructuralassignmentofisoselagintamarlinafromselaginellatamariscinaanditsbiomimeticsynthesis
AT liujiangxin isolationstructuralassignmentofisoselagintamarlinafromselaginellatamariscinaanditsbiomimeticsynthesis
AT zhaoqinshi isolationstructuralassignmentofisoselagintamarlinafromselaginellatamariscinaanditsbiomimeticsynthesis

Ejemplares similares