Impact of Ancestral Differences and Reassessment of the Classification of Previously Reported Pathogenic Variants in Patients With Brugada Syndrome in the Genomic Era: A SADS-TW BrS Registry

Brugada syndrome (BrS) is a heritable disease that results in sudden cardiac death. In the exome/genomic era, certain reported pathogenic variants in some genetic diseases have been reclassified as benign owing to their high frequency in some ancestries. In the present study, we comprehensively reas...

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Detalles Bibliográficos
Autores principales: Chen, Ching-Yu Julius, Lu, Tzu-Pin, Lin, Lian-Yu, Liu, Yen-Bin, Ho, Li-Ting, Huang, Hui-Chun, Lai, Ling-Ping, Hwang, Juey-Jen, Yeh, Shih-Fan Sherri, Wu, Cho-Kai, Juang, Jyh-Ming Jimmy, Antzelevitch, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328444/
https://www.ncbi.nlm.nih.gov/pubmed/30662450
http://dx.doi.org/10.3389/fgene.2018.00680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328444/
https://www.ncbi.nlm.nih.gov/pubmed/30662450
http://dx.doi.org/10.3389/fgene.2018.00680

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