Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis

Rheumatoid arthritis (RA) associated anti-citrullinated protein autoantibodies (ACPA) target a wide range of modified proteins. Citrullination occurs during physiological processes such as apoptosis, yet little is known about the interaction of ACPA with nuclear antigens or apoptotic cells. Since un...

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Detalles Bibliográficos
Autores principales: Lloyd, Katy A., Wigerblad, Gustaf, Sahlström, Peter, Garimella, Manasa G., Chemin, Karine, Steen, Johanna, Titcombe, Philip J., Marklein, Bianka, Zhou, Diana, Stålesen, Ragnhild, Ossipova, Elena, Lundqvist, Christina, Ekwall, Olov, Rönnelid, Johan, Mueller, Daniel L., Karlsson, Mikael C. I., Kaplan, Mariana J., Skriner, Karl, Klareskog, Lars, Wermeling, Fredrik, Malmström, Vivianne, Grönwall, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328449/
https://www.ncbi.nlm.nih.gov/pubmed/30662440
http://dx.doi.org/10.3389/fimmu.2018.03033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328449/
https://www.ncbi.nlm.nih.gov/pubmed/30662440
http://dx.doi.org/10.3389/fimmu.2018.03033

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